Key Takeaways Look for a firm band, wide adjustable straps, full-coverage cups, and one-hand access in a nursing bra for large breasts. The 24/7® Classic, Organic Cloud Cotton Wireless, and Kindred Bravely Signature Sublime Contour are the top three supportive picks. Underwire adds lift and separation, while wireless flexes with your changing fullness, so you might want one of each.