Abstract The peripheral nervous system serves as a critical interface between the brain and the immune system, orchestrating bidirectional communication that maintains homeostasis and coordinates host defense responses. Peripheral neuroimmune crosstalk occurs through multiple anatomical pathways, including autonomic efferents, sympathetic circuits, and sensory afferents that detect tissue perturbation. Among these pathways, the vagus nerve has […] The post Vagal neuroimmune circuits in inflammation and immunity appeared first on SetPoint Medical .