Cellular response to stress New and Updated Topics and Pathways. Topics with new or revised pathways in this release include Cellular responses to stimuli ( High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells , Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells , Mitochondrial unfolded protein response (mtUPR) ), Disease ( Disease of branched-chain amino acid catabolism ), Gene Expression ( Epigenetic regulation of gene expression by MLL3 and MLL4 complexes , Epigenetic regulati
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