Respiratory Syncytial Virus Infection Pathway New and Updated Topics and Pathways. As we head into winter and medical experts warn, once again, of a potential tripledemic of flu, COVID-19, and Respiratory Syncytial Virus (RSV), Reactome completes its coverage of these three viruses with the release of the RSV infection pathway in V87. Additional topics with new or revised pathways in this release include Cellular responses to stimuli ( Cellular response to mitochondrial stress ), Developmental Biology ( Kidney formation and Specification of the neural plate border ), Disease ( Defects of plate