Performance of a cfDNA methylation–based MCED test in patients with clinicoradiologic suspicion of cancer

ASCO Annual Meeting 2026 Radiographic findings suspicious for malignancy can trigger prolonged, inconclusive diagnostic workups, and the performance of cfDNA methylation–based MCED assays in this diagnostic setting remains less well characterized than in asymptomatic screening populations. This study found that, at a prespecified 98.5% specificity threshold, the Harbinger assay showed comparable specificity and sensitivity in […] The post Performance of a cfDNA methylation–based MCED test in patients with clinicoradiologic suspicion of cancer appeared first on Harbinger Health .