A $100 million shadow economy has emerged in the on-chain gray-market peptide industry, surging past a $100 million annual run rate in recent months. Over the past few years, a revolution in mainstream medicine has changed how people approach weight loss and physical enhancement, with GLP-1 compounds like those in Ozempic and Wegovy dominating public attention. Because these injections are often prohibitively expensive or unavailable due to global supply shortages, many consumers have turned to gray-market peptide alternatives paid for with cryptocurrency.