We are pleased to announce general availability of Amazon EC2 P4de instances in Asia Pacific (Tokyo, Singapore) and Europe (Frankfurt) on SageMaker Studio notebooks. Amazon EC2 P4de instances are powered by 8 NVIDIA A100 GPUs with 80GB high-performance HBM2e GPU memory, 2X higher than the GPUs in our current P4d instances. The new P4de instances provide a total of 640GB of GPU memory, which provide up to 60% better ML training performance along with 20% lower cost to train when compared to P4d instances.