Mind the Loss: Formulation optimization reduces cannula-associated vector loss during precision AAV brain delivery

In this poster presented at ASGCT 2026, Philipp Beck explores how formulation optimization can reduce vector loss during direct AAV delivery to the brain. Convection-enhanced delivery uses long, ultra-thin cannulas to administer gene therapies into highly localized regions of the central nervous system. While this approach enables precise dosing, the large surface area inside the Read More The post Mind the Loss: Formulation optimization reduces cannula-associated vector loss during precision AAV brain delivery appeared first on Ascend .