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Optimize Nextflow Workflows on AWS Batch with Mountpoint for Amazon S3

calendar_today January 13, 2026 person Michael Mueller domain amazon-simspace-weaver

Are you running genomic workflows with Nextflow on AWS Batch and experiencing bottlenecks when staging large reference files? In this post, we will show you how to optimize your workflow performance by leveraging Mountpoint for Amazon S3 to stream reference data directly into your Nextflow processes, eliminating the need to stage large static files repeatedly.

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