Amazon SageMaker HyperPod Inference Gateway is a Kubernetes-native, GPU-aware routing system that deploys as a single EKS managed add-on on existing SageMaker HyperPod infrastructure with zero application changes. By replacing unintelligent round-robin load balancing with real-time inference-signal-driven routing, it reduces first-token latency by up to 82% and p99 TTFT reductions of 97–98% in mixed-hardware and burst traffic scenarios. The Gateway is built around 3 core components.